uncle
zii
DZEE-oh
Zio takes 'lo' (not 'il') because it begins with z. Gli zii (plural) can mean 'the uncles' or 'the uncle and aunt' together. The informal 'zio!' is also used among friends meaning 'mate/dude'.
Mio zio vive a New York da molti anni.
My uncle has lived in New York for many years.
Gli zii vengono sempre a cena il sabato sera.
The aunts and uncles always come to dinner on Saturday evenings.