Is there a safe in the room?
cas-sa-FOR-te — four syllables, stress on the third.
Ask at check-in or upon entering your room if you are travelling with valuables, documents, or large amounts of cash.
'Cassaforte' literally means 'strong box' — 'cassa' (box/chest) + 'forte' (strong). It is a compound noun. 'C'è' (there is) is the standard way to ask about the existence or presence of something in Italian.
Avete una cassaforte alla reception?
Do you have a safe at reception?
Smaller hotels may only offer a safe at the front desk
Posso depositare i valori in cassaforte?
Can I deposit valuables in the safe?
Use when asking about a safe at the front desk
Come funziona la cassaforte?
How does the safe work?
Ask when the in-room safe has an unfamiliar digital lock
Italian hotels are not responsible for valuables left in the room ('oggetti lasciati incustoditi in camera'). The in-room safe or the front desk safe are your best options. Keep your passport in the safe when not needed — it is your most important document abroad.