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PhrasesAllergies and MedicationsSono allergico alla codeina.
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Sono allergico alla codeina.

I am allergic to codeine.

Pronunciation

ko-de-I-na — four syllables, stress on third. Internationally recognised term.

When to use it

Tell any doctor prescribing cough medicines, painkillers, or anaesthetic medications. Codeine is found in combined products.

What it means

'Codeina' = codeine — an opioid used in cough syrups ('sciroppi per la tosse') and combined painkillers. Codeine allergy can cause urticaria, angioedema, or anaphylaxis. Patients with codeine allergy should avoid related opioids. In Italy, codeine-containing cough syrups are prescription-only ('ricetta obbligatoria'). CYP2D6 'poor metabolisers' do not convert codeine to morphine — so it is ineffective for them rather than causing allergy.

Variations

Ho una reazione agli oppioidi in generale.

I have a reaction to opioids in general.

Broader opioid intolerance — affects choice of post-operative pain management

La morfina mi dà nausea intollerabile.

Morphine gives me intolerable nausea.

Opioid-induced nausea — an adverse effect, not necessarily true allergy

Posso prendere il tramadolo invece della codeina?

Can I take tramadol instead of codeine?

Tramadol is an alternative opioid — but cross-reactions are rare, usually safe

Mini Dialogue

— Sono allergico alla codeina. Me la sono vista prescritta nello sciroppo per la tosse. — Che reazione ha avuto? — Orticaria intensa e difficoltà a respirare. — È una vera allergia. Le evito la codeina e tutti i farmaci correlati per sicurezza. — Cosa posso prendere per la tosse? — Le do un antitussivo senza oppioidi. La destrometorfano è una buona alternativa.

— I am allergic to codeine. I saw it prescribed in a cough syrup. — What reaction did you have? — Intense hives and difficulty breathing. — It is a true allergy. I will avoid codeine and all related medications to be safe. — What can I take for a cough? — I will give you a cough suppressant without opioids. Dextromethorphan is a good alternative.

Cultural Note

Codeine is classified as a controlled substance in Italy and requires a special prescription ('ricetta stupefacenti') for pure codeine preparations. However, it is contained in combination products (cough syrups, some analgesics) at lower doses that require regular prescriptions. Italy strictly controls opioid prescribing — pharmacists log all controlled substance dispensing in national registries. Italian palliative care specialists ('cure palliative') advocate for better opioid access for terminal patients.