What is it near?
vi-CI-no a KO-sa — stress on second syllable of each key word.
Ask this when someone tells you a place is in a certain area but you need a more specific landmark to find it.
Vicino a cosa si trova (near what is it located) — vicino a (near to), cosa (what), si trova (is located, reflexive of trovarsi). This question asks for a point of reference — a landmark, shop, or well-known building near the destination.
Che punto di riferimento c'è vicino?
What landmark is there nearby?
Punto di riferimento (reference point/landmark) — more formal phrasing
C'è qualcosa di famoso vicino?
Is there something famous nearby?
Qualcosa di famoso — something recognizable to help you orient
Tra quali vie si trova?
Between which streets is it located?
Asking for the cross-street reference — useful in grid-pattern cities
In Italian cities, churches are the primary navigational landmarks — virtually every Italian can direct you relative to the nearest church, and church names rarely change over centuries unlike street names which are sometimes renamed for political reasons.